Cognitive and functional deficits are associated with white matter abnormalities in two independent cohorts of patients with schizophrenia.
Shinichi YamadaShun TakahashiBerend MalchowIrina PapazovaSophia StöckleinBirgit Ertl-WagnerBoris PapazovUlrike KumpfThomas WobrockKatriona Keller-VaradyAlkomiet HasanPeter FalkaiElias WagnerFlorian J RaabeDaniel KeeserPublished in: European archives of psychiatry and clinical neuroscience (2021)
We provide robust evidence for WM microstructural abnormalities in SZ. These abnormalities are more prominent in patients with low cognitive performance and are associated with the level of functioning.