Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation.

Nan ZhaoXiaomeng XuYongjun JiangJie GaoFang WangXiaohui XuZhuoyu WenYi XieJuanji LiRongrong LiQiushi LvQian LiuQiliang DaiXinfeng LiuGelin Xu

Published in: Journal of neuroinflammation (2019)

The results indicated a novel pattern of astrocyte activation after ischemic stroke and lipocalin-2 (LCN2) plays a key role in polarizing and activating astrocytes.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
brain injury
blood brain barrier
signaling pathway
atrial fibrillation