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Complete genome sequence of human papillomavirus 31 isolated from the human cervical cell line, CIN612 9E.

Dan ChenSimran KhuranaAlison A McBride
Published in: Microbiology resource announcements (2024)
Human papillomavirus genomes replicate extrachromosomally in infected tissues and derived keratinocyte cells. The cell line CIN12 9E was established from a cervical CIN1 lesion, contains replicating HPV31 genomes, and is widely used as a model to study the HPV life cycle. Here, we clone and sequence the HPV31 9E genome.
Keyphrases
  • high grade
  • life cycle
  • induced apoptosis
  • endothelial cells
  • cervical cancer screening
  • cell cycle arrest
  • gene expression
  • induced pluripotent stem cells
  • genome wide
  • dna methylation
  • cell death