Longevity of Post-Explantation Systemic Symptom Improvement and Potential Etiologies: Findings From the ASERF Systemic Symptoms in Women - Biospecimen Analysis Study: Part 4.

Parts 1-3 in this series concluded there were no consistent differences in biospecimen results between the cohorts. Unlike the data observed in the biospecimen analysis, BII subjects had heightened symptoms and poorer PROMIS scores at baseline compared to the control cohorts. The reduction of negative expectations and a potential nocebo effect could contribute to this improvement.