Dual-centre evaluation of the FluoroType MTBDR version 2 assay for detection of Mycobacterium tuberculosis complex and resistance-conferring mutations in pulmonary and extrapulmonary samples from Denmark, Germany and Sierra Leone.

Erik SvenssonHannah KetelsenSönke AndresDorte Bek FolkvardsenDoris HillemannOusman ContehAnders NormanStefan NiemannTroels LillebaekMartin Kuhns

Published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2024)

FTv2 reliably detects MTBC DNA in pulmonary and extrapulmonary samples and detects resistance mutations for INH and RIF resistance in inhA promoter, katG, and rpoB genes.

Keyphrases

mycobacterium tuberculosis
pulmonary hypertension
pulmonary tuberculosis
dna methylation
gene expression
genome wide
transcription factor
high throughput
single molecule
psychometric properties
loop mediated isothermal amplification
genome wide analysis