6q deletion is frequent but unrelated to patient prognosis in breast cancer.

Patrick LebokHannah BönteMartina KluthChristina Möller-KoopIsabell WitzelLinn WölberPeter PaluchowskiChristian WilkeUwe HeilenkötterVolkmar MüllerBarbara SchmalfeldtRonald SimonGuido SauterLuigi TerraccianoRainer Horst KrechAlbert von der AssenEike Burandt

Published in: Breast cancer (Tokyo, Japan) (2021)

Our data demonstrate that 6q deletion is a frequent event in breast cancer that is statistically linked to unfavorable tumor phenotype and features of genomic instability. The absence of any prognostic impact argues against a clinical applicability of 6q15 deletion testing in breast cancer patients.

Keyphrases

case report
electronic health record
big data
copy number
machine learning
dna methylation
deep learning
genome wide