CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients.

Xuewen XiaoTianyan XuHui LiuXixi LiuXinxin LiaoYafang ZhouLu ZhouXin WangYuan ZhuQijie YangXiaoli HaoYingzi LiuJiang Hong Ji-Feng Guo Jun-Ling Wang Bei-Sha TangJinchen LiLu Shen Bin Jiao

Published in: Annals of clinical and translational neurology (2022)

Our finding extended the genotype and phenotype of the CYLD gene and demonstrated that CYLD rare damaging variants may be implicated in AD and FTD pathogenesis.

Keyphrases

copy number
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
genome wide
patient reported outcomes