Bariatric surgery alters mitochondrial function in gut mucosa.

Robert C RossElizabeth C HeintzElizabeth R M ZunicaR Leigh TownsendAmanda E SpencePhilip R SchauerJohn P KirwanChristopher L AxelrodVance L Albaugh

Published in: Surgical endoscopy (2023)

Ileal interposition decreases mitochondrial volume in the proximal intestinal mucosa of mice. This change in concentration with preserved respiration suggests a global mucosal response to segment specific nutrition signals in the distal bowel. Future studies are required to understand the causes underlying these mitochondrial changes.

Keyphrases

bariatric surgery
oxidative stress
weight loss
physical activity
current status
minimally invasive
high fat diet induced
metabolic syndrome
adipose tissue
skeletal muscle