Predictors of intracranial hemorrhage in patients with atrial fibrillation treated with oral anticoagulants: Insights from the GARFIELD-AF and ORBIT-AF registries.

Toon Wei Lim Alan John CammSaverio VirdoneDaniel E SingerJean P BassandGregory Y H LipKeith A A FoxMichael EzekowitzBernard J GershGloria KayaniElaine M HylekAjay K KakkarKenneth W MahaffeyKaren S PieperEric D PetersonJonathan P Piccininull null

Published in: Clinical cardiology (2023)

Age, prior ischemic events, concomitant AP therapy, and CKD were important risk factors for ICH in anticoagulated AF patients. Moreover, ICH was more frequent in patients receiving VKA compared to NOAC. The new validated model is a step toward mitigating this potentially lethal complication.

Keyphrases

atrial fibrillation
oral anticoagulants
end stage renal disease
chronic kidney disease
newly diagnosed
transcription factor
stem cells
patient reported outcomes
ischemia reperfusion injury
optical coherence tomography