Severity of infection with the SARS-CoV-2 B.1.1.7 lineage among hospitalized COVID-19 patients in Belgium.
Nina Van GoethemMathil VandrommeHerman Van OyenFreek HaarhuisRuben BrondeelLucy CatteauEmmanuel AndréLize Cuypersnull nullnull nullKoen BlotBen SerrienPublished in: PloS one (2022)
This matched observational cohort study did not find an overall increased risk of severe COVID-19 or death associated with B.1.1.7 infection among patients already hospitalized. There was a significant increased risk to be transferred to ICU when infected with the B.1.1.7 variant, especially among the younger age group. However, potential selection biases advocate for more systematic sequencing of samples from hospitalized COVID-19 patients.