Immunomodulatory placental-expanded, mesenchymal stromal cells improve muscle function following hip arthroplasty.

Tobias WinklerCarsten PerkaPhilipp von RothAlison N AgresHenning PlageBernd PreiningerMatthias PumbergerSven GeisslerEsther Lukasiewicz HagaiRacheli OfirLena PinzurEli EyalGisela Stoltenburg-DidingerChristian MeiselChristine ConsentiusMathias StreitzPetra ReinkeGeorg N DudaHans-Dieter Volk

Published in: Journal of cachexia, sarcopenia and muscle (2018)

Allogeneic PLX-PAD therapy improved strength and volume of injured skeletal muscle with a reasonable safety profile. Outcomes could be positively correlated with the modulation of early postoperative stress-related immunological reactions.

Keyphrases

skeletal muscle
bone marrow
stem cell transplantation
insulin resistance
patients undergoing
total hip arthroplasty
stress induced
mesenchymal stem cells
type diabetes
adipose tissue
glycemic control
drug induced