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Whole-genome resequencing of Chinese indigenous sheep provides insight into the genetic basis underlying climate adaptation.

Meilin JinHuihua WangGang LiuJian LuZehu YuanTaotao LiEngming LiuZengkui LuLixin DuCaihong Wei
Published in: Genetics, selection, evolution : GSE (2024)
Analysis of the signatures of selection uncovered genes that are likely related to environmental adaptation and a SNP missense mutation in the TSHR gene that affects the protein structure and stability. It also provides information on the evolution of the phylogeographic structure of Chinese indigenous sheep populations. These results provide important genetic resources for future breeding studies and new perspectives on how animals can adapt to climate change.
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