Progressive supranuclear palsy is not associated with neurogenic orthostatic hypotension.
Jay A van GerpenRana Hanna Al-ShaikhPhilip Wade TiptonZbigniew K WszolekRyan J UittiTanis J FermanGourisankar GhoshEduardo E BenarrochWolfgang SingerJeremy K Cutsforth-GregoryMichael G HeckmanDanielle E BrushaberKeith Anthony JosephsPhillip A LowJ Eric AhlskogWilliam P CheshirePublished in: Neurology (2019)
Our results suggest that the cardiovascular adrenergic system, which sustains BP during standing, is relatively unaffected, if not spared, in PSP. These findings increase our understanding of the clinical signature of PSP and have the potential to improve diagnostic accuracy in atypical parkinsonisms by distinguishing PSP from the α-synucleinopathies.