Increased IFN-γ + and TNF-α + mucosal-associated invariant T cells in patients with aplastic anemia.

Xiaohui ChenYuping ZhangYi-Kai Zhang Yue ZhangShunqing WangZhi YuXiaoen Liu Guixuan HuangLixing GuoXueqin LiXianfeng ZhaYangqiu Li Bo Li

Published in: Cytometry. Part B, Clinical cytometry (2023)

We present the first observation of MAIT cells in patients with AA. MAIT cells are associated with a higher frequency of IFN-γ and TNF-α production and may contribute to the pathogenesis of AA.

Keyphrases

induced apoptosis
cell cycle arrest
rheumatoid arthritis
immune response
dendritic cells
signaling pathway
endoplasmic reticulum stress
cell death
acute myeloid leukemia
allogeneic hematopoietic stem cell transplantation
cell proliferation
pi k akt
ulcerative colitis