Variation in hypertension clinical practice guidelines: a global comparison.
Richu PhilipThomas BeaneyNick AppelbaumCarmen Rodriguez GonzalvezCharlotte KoldeweijAmelia Kataria GolestanehNeil PoulterJonathan M ClarkePublished in: BMC medicine (2021)
This study found that CPGs remained largely consistent in the definition, staging and target BP recommendations for hypertension. Extensive variation was observed in treatment recommendations, particularly for second-line therapy. Variation existed between income settings; low-income countries prescribed cheaper drugs, offered less clinician choice in medications and initiated dual therapy at later stages than higher-income countries. Future research exploring the underlying drivers of this variation may improve outcomes for hypertensive patients across clinical contexts.