Costimulatory checkpoint SLAMF8 is an independent prognosis factor in glioma.

Cun-Yi ZouGe-Fei GuanChen ZhuTian-Qi LiuQing GuoWen ChengAn-Hua Wu

Published in: CNS neuroscience & therapeutics (2018)

Our study highlighted the important role of SLAMF8 in malignancy progression, shortened survival, and immune disorders. Further research on SLAMF8 in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.

Keyphrases

oxidative stress
dna damage
cell cycle