Decreased Frontal Gamma Activity in Alzheimer Disease Patients.

Elias Paolo CasulaMaria C PellicciariSonia BonnìIlaria BorghiMichele MaiellaMartina AssognaMarilena MineiCaterina MottaAlessia D'AcuntoFrancesco PorrazziniValentina PezzopaneLucia MencarelliAndrea RoncaioliLorenzo RocchiDanny A SpampinatoCarlo CaltagironeEmiliano SantarnecchiAlessandro MartoranaGiacomo Koch

Published in: Annals of neurology (2022)

Our data provide novel evidence that frontal lobe gamma activity is dampened in AD patients. The current results point to the TMS-EEG approach as a promising technique to measure individual frontal gamma activity in patients with AD. This index could represent a useful biomarker to predict disease progression and to evaluate response to novel pharmacological therapies. ANN NEUROL 2022;92:464-475.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
working memory
functional connectivity
chronic kidney disease
peritoneal dialysis
prognostic factors
resting state
machine learning
electronic health record