Microglial contribution to synaptic uptake in the prefrontal cortex in schizophrenia.

Makis TziorasA J StevensonDelphine Boche Tara L Spires-Jones

Published in: Neuropathology and applied neurobiology (2020)

Microglia in human post-mortem tissue in schizophrenia patients' brains engulf synaptic material, but not differently to age-matched non-neurological control brains. Also, schizophrenia brains display similar levels of microgliosis to control brains.

Keyphrases

prefrontal cortex
bipolar disorder
end stage renal disease
inflammatory response
ejection fraction
endothelial cells
chronic kidney disease
newly diagnosed
neuropathic pain
lipopolysaccharide induced
spinal cord injury
patient reported outcomes
brain injury