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Multilineage involvement in KMT2A-rearranged B acute lymphoblastic leukaemia: cell-of-origin, biology, and clinical implications.

Umut AyparDeepika DilipRamya GaddeDory M LondonoYing LiuQi GaoMark B GeyerAndriy DerkachYanming ZhangJacob L GlassMikhail RoshalWenbin Xiao
Published in: Histopathology (2024)
In summary, multilineage involvement is common in both BCR::ABL1-rearranged and KMT2A-rearranged B-ALL, which should be taken into consideration when interpreting the disease burden during the clinical course.
Keyphrases
  • tyrosine kinase
  • chronic myeloid leukemia
  • liver failure
  • acute lymphoblastic leukemia
  • single cell
  • cell therapy
  • respiratory failure
  • drug induced
  • risk factors
  • intensive care unit