Immune-mediated thrombotic thrombocytopenic purpura in patients with and without systemic lupus erythematosus: a retrospective study.

Cai YueJian SuXiaohong FanLi SongWei JiangJinghua XiaTao ShiXuan ZhangXuemei Li

Published in: Orphanet journal of rare diseases (2020)

Renal involvement was less severe in patients with SLE-TTP than in patients with primary iTTP. The treatment responses and outcomes of SLE-TTP were no worse and perhaps even better than those of primary iTTP. When TTP is diagnosed in SLE patients, the ADAMTS13 level and ADAMTS13 inhibitor profile should be considered in addition to clinical features.

Keyphrases

systemic lupus erythematosus
disease activity
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
drug induced