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Urinary and Serum Angiogenic Markers in Women With Preexisting Diabetes During Pregnancy and Their Role in Preeclampsia Prediction.

Monica ZenSuja PadmanabhanKewei ZhangAdrienne KirbyNgai Wah CheungVincent W LeeThushari I Alahakoon
Published in: Diabetes care (2019)
This study prospectively describes the longitudinal changes in urinary PlGF alongside serum angiogenic markers throughout pregnancy in women with preexisting diabetes. We demonstrate correlation between urinary and serum PlGF and that in women with preexisting diabetes in pregnancy, serum PlGF is a better predictor of preeclampsia than the sFLT-1-to-PlGF ratio.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • pregnancy outcomes
  • preterm birth
  • pregnant women
  • adipose tissue
  • insulin resistance
  • skeletal muscle