Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.
Grazia PalombaValentina DonedduAntonio CossuPanagiotis PaliogiannisAntonella MancaMilena CasulaMaria ColombinoAnnamaria LanzilloEfisio DefraiaAntonio PazzolaGiovanni SannaCarlo PutzuSalvatore OrtuMario ScartozziMaria Teresa IontaGiovanni BaldinoGiuseppina SarobbaFrancesca CapelliTito SeddaLuciano VirdisMichela BarcaGiulia GramignanoMario BudroniFrancesco TandaGiuseppe PalmieriPublished in: Journal of translational medicine (2016)
Our study defines both prevalence and prognostic role of main activated oncogenes in a population-based large collection of CRC patients.