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Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.

Grazia PalombaValentina DonedduAntonio CossuPanagiotis PaliogiannisAntonella MancaMilena CasulaMaria ColombinoAnnamaria LanzilloEfisio DefraiaAntonio PazzolaGiovanni SannaCarlo PutzuSalvatore OrtuMario ScartozziMaria Teresa IontaGiovanni BaldinoGiuseppina SarobbaFrancesca CapelliTito SeddaLuciano VirdisMichela BarcaGiulia GramignanoMario BudroniFrancesco TandaGiuseppe Palmieri
Published in: Journal of translational medicine (2016)
Our study defines both prevalence and prognostic role of main activated oncogenes in a population-based large collection of CRC patients.
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