Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2 -Overexpressing Metastatic Breast Cancer.

Charles L VogelMelody A CobleighDebu TripathyJohn C GutheilLyndsay N HarrisLouis FehrenbacherDennis J SlamonMaureen MurphyWilliam F NovotnyMichael BurchmoreSteven ShakStanford J StewartMichael Press

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)

3+ overexpression by IHC or gene amplification by FISH.

Keyphrases

metastatic breast cancer
copy number
cell proliferation
nucleic acid
genome wide
transcription factor
genome wide identification
dna methylation
gene expression
label free