Enzymatically stable analogue of the gut-derived peptide xenin on beta-cell transdifferentiation in high fat fed and insulin-deficient Ins1Cre/+ ;Rosa26-eYFP mice.

Neil TandayR Charlotte MoffettVictor A GaultPeter R FlattNigel Irwin

Published in: Diabetes/metabolism research and reviews (2020)

Benefits of xenin-25[Lys13 PAL] on diabetes includes positive modulation of islet cell differentiation, in addition to promoting beta-cell growth and survival.

Keyphrases

type diabetes
glycemic control
single cell
cardiovascular disease
high fat diet induced
wild type
free survival
insulin resistance
adipose tissue
bone marrow