Lower serum alpha 1 antitrypsin levels in patients with severe COVID-19 compared with patients hospitalized due to non-COVID-19 pneumonia.

Barak Pertzov Guy ShapiraSimon AbushkaraSharon CohenAdi TurjemanMordechai R KramerDavid Gurwitz Noam Shomron

Published in: Infectious diseases (London, England) (2022)

Patients admitted due to severe COVID-19 had lower A1AT levels in comparison to patients admitted due to non-COVID pneumonia. This observation may suggest an association between mildly diminished A1AT and higher risk of SARS-CoV-2 infection with severe COVID-19 disease.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
end stage renal disease
early onset
chronic kidney disease
ejection fraction
intensive care unit
drug induced
prognostic factors
community acquired pneumonia
patient reported