Randomized controlled pilot study assessing fructose tolerance during fructose reintroduction in non-constipated irritable bowel syndrome patients successfully treated with a low FODMAP diet.

Callie CuffLisa D LinSwapna Mahurkar-JoshiJonathan P JacobsVenu LagishettyNancee JaffeJanelle SmithTien DongJessica SohnLin Chang

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)

Non-constipated, LFD-responsive IBS patients should be reintroduced to fructose in higher doses than 15 g to assess tolerance. LFD is associated with significant changes in microbial composition and bacterial genes involved in FODMAP metabolism.

Keyphrases

irritable bowel syndrome
end stage renal disease
chronic kidney disease
ejection fraction
peritoneal dialysis
microbial community
prognostic factors
physical activity
open label
cancer therapy
phase iii