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Minisci-Type Dehydrogenative Coupling of C(sp 3 )-H and N-Heteroaromatics Enabled by Photoelectrochemical Hydrogen Atom Transfer.

Kaikai QiaoJun-Feng YangZhi ChenYong ZhuWen-Feng JiangFei LiLei Shi
Published in: Organic letters (2024)
Minisci-type dehydrogenative coupling of C(sp 3 )-H and N-heteroaromatics was performed with N -hydroxysuccinimide as a hydrogen atom transfer catalyst in a photoelectrochemical cell composed of a mesoporous BiVO 4 photoanode and a Pt electrode. In the absence of metal catalysts and chemical oxidants, a range of N -heteroarenes (e.g., quinolines, isoquinolines, and quinoxaline) can undergo coupling with various C(sp 3 )-H partners to form the corresponding products in excellent yields.
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