Beneficial effects of bardoxolone methyl, an Nrf2 activator, on crush-related acute kidney injury in rats.

Emine KadıoğluYasemin TekşenCengiz KoçakFatma Emel Koçak

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2019)

BM treatment prevented the progression of crush-related AKI in rats possibly through its cytoprotective effects of being an antioxidant, anti-inflammatory and anti-apoptotic agent.

Keyphrases

anti inflammatory
oxidative stress
cell death
acute kidney injury
liver failure
drug induced
respiratory failure
immune response
inflammatory response
hepatitis b virus
extracorporeal membrane oxygenation
combination therapy
acute respiratory distress syndrome
replacement therapy
mechanical ventilation