Comparison of Bio-C Pulpo and MTA Repair HP with White MTA: effect on liver parameters and evaluation of biocompatibility and bioactivity in rats.

Mateus Machado DelfinoJosé Leandro de Abreu JampaniCamila Soares LopesJuliane M Guerreiro-TanomaruMario Tanomaru-FilhoEstela Sasso-CerriPaulo Sergio Cerri

Published in: International endodontic journal (2021)

Bio-C Pulpo, MTA-HP and WMTA materials did not cause morphological changes in the liver and no significant alteration in the serum GOT and GPT levels. Moreover, these bioceramic materials were biocompatible and exhibited bioactive potential. However, Bio-C Pulpo induced greater inflammatory infiltrate than MTA-HP and WMTA at all periods.

Keyphrases

oxidative stress
high glucose
diabetic rats
ionic liquid
risk assessment
endothelial cells