Neurodegenerative disease pathways are perturbed in patients with cancer who self-report cognitive changes and anxiety: A pathway impact analysis.

Kate R Oppegaard Samantha J Mayo Terri S ArmstrongVasuda DokiparthiMichelle MeliskoJon D LevineAdam B OlshenJoaquin A Anguera Ritu Roy Steven M Paul Bruce A Cooper Yvette P Conley Marilyn J Hammer Christine A Miaskowski Kord M Kober

Published in: Cancer (2024)

This study is the first to describe perturbations in neurodegenerative disease pathways associated with CRCI and anxiety in patients receiving chemotherapy. These findings provide new insights into potential targets for the development of mechanistically based interventions.

Keyphrases

sleep quality
physical activity
squamous cell carcinoma
locally advanced
radiation therapy
climate change
human health
rectal cancer