The methanol extract of Guettarda speciosa Linn. Ameliorates acute lung injury in mice.

Kyun Ha KimJi Yeon LeeSeonju AhnRan WonSang-Jun KimSeung-Il JeongJung Ju LeeJong-In KimJun-Yong ChoiMyungsoo Joo

Published in: BMC complementary medicine and therapies (2020)

MGS could suppress lung inflammation in an ALI mouse model, the effect of which could be attributed to multiple mechanisms, including the activation of Nrf2 and the suppression of NF-κB and neutrophil elastase enzymatic activity by MGS.

Keyphrases

oxidative stress
mouse model
lps induced
lipopolysaccharide induced
inflammatory response
high fat diet induced
hydrogen peroxide
signaling pathway
carbon dioxide
pi k akt
metabolic syndrome
cell proliferation
adipose tissue
anti inflammatory