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The Spike-and-Slab Lasso regression modeling with compositional covariates: An application on Brazilian children malnutrition data.

Francisco LouzadaTaciana Ko ShimizuAdriano K Suzuki
Published in: Statistical methods in medical research (2019)
There are considerable challenges in analyzing large-scale compositional data. In this paper, we introduce the Spike-and-Slab Lasso linear regression in the presence of compositional covariates for parameter estimation and variable selection. We consider the well-known isometric log-ratio (ilr) coordinates to avoid misleading statistical inference. The separable and non-separable (adaptative) Spike-and-Slab Lasso penalties are compared to verify the advantages of each approach. The proposed method is illustrated on simulated and on real Brazilian child malnutrition data.
Keyphrases
  • electronic health record
  • big data
  • young adults
  • mental health
  • single cell
  • artificial intelligence