Relationship between metformin use and vitamin B12 status in patients with type 2 diabetes in Japan.

Kenji Sugawara Yuko Okada Yushi Hirota Kazuhiko Sakaguchi Wataru Ogawa

Published in: Journal of diabetes investigation (2020)

The risk of VB12 deficiency during metformin treatment appears to be low in Japanese type 2 diabetes mellitus patients. However, high doses of metformin might result in a moderate decrease in the circulating VB12 level, as well as in anemia in elderly individuals.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
peritoneal dialysis
prognostic factors
cardiovascular disease
type diabetes
high intensity
middle aged
adipose tissue
insulin resistance
iron deficiency
patient reported
community dwelling