A case-control survey study of environmental risk factors for primary hypoadrenocorticism in dogs.
Amy E TreefulKelly M SearleDana M CarrollKathleen J YostAnna L HedgerSteven G FriedenbergPublished in: Journal of veterinary internal medicine (2023)
The large effect size for reproductive status reflects its high potential clinical relevance, whereas modest effect sizes for other environmental variables suggest lower potential clinical relevance. These findings are associations and do not necessarily imply causation. Before any actionable recommendations are warranted, additional evidence regarding biological mechanisms is needed.