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Preparation and characterization of chitosan/poly(vinyl alcohol)/graphene oxide films and studies on their antibiofilm formation activity.

Ye YingYunbo WuJianying Huang
Published in: Journal of biomedical materials research. Part A (2020)
Biocomposite films containing graphene oxide (GO), poly(vinyl alcohol) (PVA), and chitosan (CS) were prepared using the casting/evaporation technique. These as-prepared films were characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, and scanning electron microscopy. Results showed that these three component films could be well mixed in certain conditions and the GO sheets were well dispersed. The better performances such as the water resistance, thermal stability, and mechanical properties have been improved. Meanwhile, good antibacterial activity and antibiofilm formation activity of the prepared CS/PVA/GO films were exhibited against Pseudomonas aeruginosa PAO1. The resulting biocomposite films with combination of CS, PVA, and GO advantages have desirable properties and should be suitable for food and medical packaging applications.
Keyphrases
  • room temperature
  • electron microscopy
  • pseudomonas aeruginosa
  • drug delivery
  • cystic fibrosis
  • risk assessment
  • escherichia coli
  • ionic liquid
  • drug resistant