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Investigation of neutron and gamma radiation protective characteristics of synthesized quinoline derivatives.

Bünyamin AygünBurak AlaylarKadir TurhanErdem ŞakarMehmet KaradayıMohammed Ibrahim Abu Al-SayyedEmel PelitMedine GüllüceAbdulhalik KarabulutZuhal TurgutBünyamin Alım
Published in: International journal of radiation biology (2020)
Neutron shielding parameters such as removal cross-section, mean free path, half value layer and transmission number were theoretically determined for fast neutrons. To determine neutron absorption capacity of quinoline derivatives, neutron absorption, experiments were conducted. In addition, gamma radiation shielding parameters were calculated such as the mean free path (MFP), mass attenuation coefficient (µt), half value thickness layer (HVL) and effective atomic number (Zeff) in the energy range of 0.015-15 MeV. The results of the all quinoline derivatives have excellent fast neutron shielding power compared to ordinary concrete. In addition, all quinoline derivatives have been found to have the capacity to attenuate gamma radiation. Moreover, they absorb well in both types of radiation, do not cause secondary radiation, and they are genotoxically safe at the tested concentrations. This study has demonstrated that these products can be used as active ingredients for a drug to be developed against radiation.
Keyphrases
  • molecular docking
  • radiation induced
  • emergency department
  • magnetic resonance imaging
  • radiation therapy
  • molecular dynamics simulations
  • electron microscopy