Proton pump inhibitors may reduce the risk of high-grade dysplasia and/or esophageal adenocarcinoma in Barrett's esophagus: a systematic review and meta-analysis.
Haijuan YaoLe WangHongyu LiShixue XuZhaohui BaiYanyan WuHongxin ChenHemant GoyalXing Shun QiPublished in: Expert review of clinical pharmacology (2021)
Chemoprevention of HGD and/or EAC by PPIs may be considered in BE patients. However, there might not be further preventive effect of high-dose PPIs.