ARF4-mediated retrograde trafficking as a driver of chemoresistance in GBM.
Shreya BudhirajaGraysen McManusShivani BaisiwalaElla N PerraultSia ChoMiranda SaathoffLi ChenCheol H ParkHasaan A KaziCrismita DmelloPeiyu LinC David JamesAdam M SonabendDieter H HeilandAtique U AhmedPublished in: Neuro-oncology (2024)
Our findings demonstrate that ARF4-mediated retrograde trafficking contributes to the development of TMZ resistance, cementing this pathway as a viable strategy to overcome chemoresistance in GBM.
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