Primary Tumor Suppression and Systemic Immune Activation of Macrophages through the Sting Pathway in Metastatic Skin Tumor.
Chun-Bong SynnDong Kwon KimSeok-Young KimYoungseon ByeonYoung Seob KimMi Ran YunJi Min LeeWongeun LeeEun Ji LeeSeul LeeYou Won LeeDoo Jae LeeHyun-Woo KimChang Gon KimMin Hee HongJune Dong ParkSun Min LimKyoung-Ho PyoPublished in: Yonsei medical journal (2021)
The abscopal effect of DMXAA treatment on the skin strongly reduced the spread of EML4-ALK lung cancer and CT26 colon cancer through the STING pathway and induced the presentation of antigens.