A Fixed versus Weight-Based Dosing Strategy of Daptomycin May Improve Safety in Obese Adults.

Jill M Butterfield-CowperThomas P LodiseManjunath Amit P Pai

Published in: Pharmacotherapy (2018)

Weight-based maintenance dosing of daptomycin is less likely to yield bioequivalent exposures in morbidly obese subjects and provides credence for the evaluation of fixed maintenance doses across adult body size to improve safety.

Keyphrases

weight loss
bariatric surgery
obese patients
adipose tissue
body mass index
metabolic syndrome
methicillin resistant staphylococcus aureus
physical activity
type diabetes
weight gain
air pollution
young adults