DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy.

Maria TsagiopoulouNikos PapakonstantinouTheodoros MoysiadisLarry MansouriViktor LjungströmMartí Duran-FerrerAndigoni MalousiAna C QueirósKarla PlevovaSujata BhoiPanagoula KolliaDavid OscierAchilles AnagnostopoulosLivio TrentinMatthias RitgenSarka PospisilovaNiki StavroyianniPaolo GhiaJose I Martin-SuberoChristiane PottRichard RosenquistKostas Stamatopoulos

Published in: Clinical epigenetics (2019)

Overall, we show that DNA methylation in CLL follows different dynamics in response to chemoimmunotherapy. These epigenetic alterations were linked with specific clinical and biological features.

Keyphrases

dna methylation
chronic lymphocytic leukemia
genome wide
gene expression
copy number