Aescin Protects against Experimental Benign Prostatic Hyperplasia and Preserves Prostate Histomorphology in Rats via Suppression of Inflammatory Cytokines and COX-2.
Mohamed RaafatAmr A KamelAlaa H ShehataAl-Shaimaa F AhmedAsmaa M A BayoumiRabab A MoussaMohammad A S AbourehabMahmoud El-DalyPublished in: Pharmaceuticals (Basel, Switzerland) (2022)
The results of this study showed, for the first time, that aescin protected against the development of experimental BPH in rats via its anti-inflammatory and antiproliferative effects. These findings warrant further studies to clinically repurpose aescin in the management of BPH.