An efficient and combined placental T 1 -ADC acquisition in pregnancies with and without pre-eclampsia.
Jana HutterAlison HoLaurence H JacksonPaddy J SlatorLucy C ChappellJoseph V HajnalMary A RutherfordPublished in: Magnetic resonance in medicine (2021)
The presented sequence allows the simultaneous acquisition of 2 of the most promising quantitative parameters to study placental insufficiency-identified individually as relevant in previous studies-in under 2 minutes. This allows dynamic assessment of physiological processes, reduced inconsistency in spatial comparisons due to reduced motion artefacts and opens novel avenues for analysis. Initial results in pre-eclamptic placentas, with depicted changes in both ADC and T 1 , illustrate its potential to identify cases of placental insufficiency. Future work will focus on expanding the field-of-view using multi-band acceleration techniques and the expansion to larger and more diverse patient groups.