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An efficient and combined placental T 1 -ADC acquisition in pregnancies with and without pre-eclampsia.

Jana HutterAlison HoLaurence H JacksonPaddy J SlatorLucy C ChappellJoseph V HajnalMary A Rutherford
Published in: Magnetic resonance in medicine (2021)
The presented sequence allows the simultaneous acquisition of 2 of the most promising quantitative parameters to study placental insufficiency-identified individually as relevant in previous studies-in under 2 minutes. This allows dynamic assessment of physiological processes, reduced inconsistency in spatial comparisons due to reduced motion artefacts and opens novel avenues for analysis. Initial results in pre-eclamptic placentas, with depicted changes in both ADC and T 1 , illustrate its potential to identify cases of placental insufficiency. Future work will focus on expanding the field-of-view using multi-band acceleration techniques and the expansion to larger and more diverse patient groups.
Keyphrases
  • diffusion weighted imaging
  • diffusion weighted
  • current status
  • high resolution
  • magnetic resonance imaging
  • gestational age
  • computed tomography
  • magnetic resonance
  • high speed
  • pregnancy outcomes
  • contrast enhanced