IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients.

Stefania CrucittaFrancesco PasqualettiAlessandra GonnelliMartina RuglioniGiovanna Irene LuculliMartina CantarellaValerio OrtenziCristian ScatenaFabiola PaiarAntonio Giuseppe NaccaratoRomano DanesiMarzia Del Re

Published in: BMC cancer (2024)

The present study demonstrates that liquid biopsy may be used in brain tumors to detect IDH1 mutation which represents an important prognostic biomarker in patients with different types of gliomas, being associated to OS.

Keyphrases

end stage renal disease
low grade
ejection fraction
chronic kidney disease
high grade
prognostic factors
peritoneal dialysis
ionic liquid
ultrasound guided
patient reported outcomes