Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndrome.
François BagateSamuel TuffetPaul MasiFrançois PerierKeyvan RazaziNicolas de ProstGuillaume CarteauxDidier PayenArmand Mekontso DessapPublished in: Annals of intensive care (2020)
In this pilot study of severe C-ARDS patients, iNO-almitrine combination was associated with rapid and significant improvement of oxygenation. These findings highlight the role of pulmonary vascular function in COVID-19 pathophysiology.
Keyphrases
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- coronavirus disease
- nitric oxide
- sars cov
- mechanical ventilation
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- early onset
- pulmonary hypertension
- cystic fibrosis
- stem cells
- intensive care unit
- respiratory syndrome coronavirus
- hydrogen peroxide
- mesenchymal stem cells
- drug induced