Moderate physical exercise improves lymphocyte function in melanoma-bearing mice on a high-fat diet.

Cesar Miguel Momesso Dos SantosVinicius Leonardo Sousa DinizAndré Luis Lacerda BachiLaiane Cristina Dos Santos de OliveiraTamara GhazalMaria Elizabeth Pereira PassosHeloisa Helena de OliveiraGilson MurataLaureane Nunes MasiAmanda Roque MartinsAdriana Cristina Levada-PiresRui CuriSandro Massao HirabaraDonald F SellittiTania Cristina Pithon-CuriRenata Gorjão

Published in: Nutrition & metabolism (2019)

The results of the present study support the hypothesis that altering function of tumor non-infiltrated lymphocytes via exercise-related mechanisms can slow melanoma progression, indicating that the incorporation of a regular practice of moderate-intensity exercises can be a potential strategy for current therapeutic regimens in treating advanced melanoma.

Keyphrases

high fat diet
high intensity
resistance training
adipose tissue
insulin resistance
skin cancer
peripheral blood
healthcare
primary care
basal cell carcinoma
high fat diet induced
type diabetes
risk assessment
skeletal muscle
wild type
drug induced