COVID-19 and hydatidiform mole.
Ahmed M A SobhLobna AhmedAmera S SalemShimaa H ElsammanAlshaima RefaiSafaa K FathyOmar A AhmedAsmaa S ShalotutRadwa A AbdelWahabPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)
The emergence of coronavirus disease 2019 (COVID-19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID-19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent pregnancy loss, and early-onset preeclampsia. In this article, we tried to summarize the possible association between COVID-19 and the HM's development by reviewing the role of NOD-Like Receptor (NLR) Family Pyrin Domain Containing 7 (NLRP7), cytokines, zinc, and leukocytes in the pathogenesis of HM.