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Identification of a novel antisense noncoding RNA, ALID, transcribed from the putative imprinting control region of marsupial IGF2R.

Shunsuke SuzukiGeoffrey ShawMarilyn B Renfree
Published in: Epigenetics & chromatin (2018)
Our study thus provides the best candidate factor for establishing paternal silencing of marsupial IGF2R without transcriptional overlap, which is distinct from the Igf2r silencing mechanism of Airn, but which may be analogous to the mode of action for the flanking Slc22a2 and Slc22a3 gene silencing in the mouse placenta.
Keyphrases
  • pi k akt
  • binding protein
  • growth hormone
  • gene expression
  • nucleic acid
  • transcription factor
  • signaling pathway
  • heat stress