Quantitative detections of TP53 gene mutations improve the diagnosis and prognostic prediction of biliary tract cancers using droplet digital PCR.

Xiao XiaoJun ZhouMeng FangJun JiChenjun HuangFei DuWenchao AiYing WangZhiyuang GaoZhiquan QiuChunfang Gao

Published in: Journal of clinical laboratory analysis (2021)

This study revealed for the first time that the quantitative TP53 mutations using the ddPCR might serve as a potential genetic biomarker for BTC diagnosis and prognosis assessment.

Keyphrases

single cell
high resolution
high throughput
genome wide
dna methylation
copy number
young adults
mass spectrometry
human health
climate change
clinical evaluation