Comparisons between diluted thrombin time, ecarin chromogenic assays, and UPLC-MS for plasma level dabigatran quantification: Results from DRIVING study.

Ambre de Fautereau-VasselAntoine MokhtarianManon MangenotOmbeline KrekounianIsabelle KousignianXavier DelavenneEmmanuel Curis Isabelle Gouin-Thibault Virginie Siguret

Published in: International journal of laboratory hematology (2023)

dTT and ECA-II assays rapidly provide accurate dabigatran-level results for clinical practice, both assays being suitable in emergency, taking into account the thrombin inhibitory effect of dabigatran metabolites.

Keyphrases

atrial fibrillation
high throughput
clinical practice
ms ms
emergency department
public health
mass spectrometry
multiple sclerosis
high resolution
simultaneous determination